About: Noretynodrel

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Noretynodrel, or norethynodrel, sold under the brand name Enovid among others, is a progestin medication which was previously used in birth control pills and in the treatment of gynecological disorders but is now no longer marketed. It was available both alone and in combination with an estrogen. The medication is taken by mouth.

Property Value
dbo:abstract
  • El noretinodrel fue la primera progestina usado en Envoid, el primer anticonceptivo oral.​​ (es)
  • Noretynodrel, or norethynodrel, sold under the brand name Enovid among others, is a progestin medication which was previously used in birth control pills and in the treatment of gynecological disorders but is now no longer marketed. It was available both alone and in combination with an estrogen. The medication is taken by mouth. Noretynodrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It is a relatively weak progestogen. The medication has weak estrogenic activity, no or only very weak androgenic activity, and no other important hormonal activity. It is a prodrug of various active metabolites in the body, such as norethisterone among others. Noretynodrel was introduced for medical use in 1957. It was specifically approved at this time in combination with mestranol for the treatment of gynecological and menstrual disorders. Subsequently, in 1960, this formulation was approved for use as a birth control pill. It was the first birth control pill to be introduced, and was followed by birth control pills containing norethisterone and other progestins shortly thereafter. Due to its nature as a relatively weak progestogen, noretynodrel is no longer used in medicine. As such, it is no longer marketed. (en)
  • 异炔诺酮(英語:Noretynodrel 或 英語:norethynodrel,商品名:Enovid等)是一种黄体制剂药物,过去被用于口服避孕药以及治疗一些妇科疾病,但现在已不再使用。异炔诺酮和炔诺酮的不同之处在于双键位于5(10)号位而非4(5)号位。 (zh)
dbo:alternativeName
  • Enovid (withmestranol), others (en)
dbo:casNumber
  • 68-23-5
dbo:chEBI
  • 34895
dbo:chEMBL
  • 1387
dbo:class
dbo:drugbank
  • DB09371
dbo:fdaUniiCode
  • 88181ACA0M
dbo:kegg
  • D05207
dbo:pubchem
  • 6231
dbo:thumbnail
dbo:wikiPageID
  • 26781411 (xsd:integer)
dbo:wikiPageLength
  • 32016 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1123032957 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • G03 (en)
dbp:atcSuffix
  • FA09 (en)
dbp:c
  • 20 (xsd:integer)
dbp:casNumber
  • 68 (xsd:integer)
dbp:chebi
  • 34895 (xsd:integer)
dbp:chembl
  • 1387 (xsd:integer)
dbp:chemspiderid
  • 5995 (xsd:integer)
dbp:class
dbp:drugbank
  • DB09371 (en)
dbp:eliminationHalfLife
  • Very short (en)
dbp:excretion
  • Breast milk: 1% (en)
dbp:h
  • 26 (xsd:integer)
dbp:image
  • Noretynodrel molecule ball.png (en)
dbp:iupacName
  • -17 (xsd:integer)
dbp:kegg
  • D05207 (en)
dbp:metabolism
  • Liver, intestines (en)
dbp:metabolites
  • • 3α-Hydroxynoretynodrel (en)
  • • 3β-Hydroxynoretynodrel (en)
  • • Ethinylestradiol• Conjugates (en)
  • • Norethisterone (en)
dbp:o
  • 2 (xsd:integer)
dbp:proteinBound
  • Noretynodrel: to albumin and not to or (en)
dbp:pubchem
  • 6231 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • O=C4CCC\1=CC4 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • ICTXHFFSOAJUMG-SLHNCBLASA-N (en)
dbp:synonyms
  • Norethynodrel; Noretinodrel Norethinodrel; NYD; SC-4642; NSC-15432; 5-Norethisterone; 17α-Ethinyl-19-nor-5-testosterone; 17α-Ethynyl-δ5-19-nortestosterone; 17α-Ethynylestr-5-en-17β-ol-3-one; 19-Nor-17α-pregn-5-en-20-yn-17β-ol-3-one (en)
dbp:title
dbp:titlestyle
  • background:#ccccff (en)
dbp:tradename
  • Enovid , others (en)
dbp:unii
  • 88181 (xsd:integer)
dbp:verifiedfields
  • verified (en)
dbp:verifiedrevid
  • 462262956 (xsd:integer)
dbp:watchedfields
  • verified (en)
dbp:width
  • 225 (xsd:integer)
  • 235 (xsd:integer)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • El noretinodrel fue la primera progestina usado en Envoid, el primer anticonceptivo oral.​​ (es)
  • 异炔诺酮(英語:Noretynodrel 或 英語:norethynodrel,商品名:Enovid等)是一种黄体制剂药物,过去被用于口服避孕药以及治疗一些妇科疾病,但现在已不再使用。异炔诺酮和炔诺酮的不同之处在于双键位于5(10)号位而非4(5)号位。 (zh)
  • Noretynodrel, or norethynodrel, sold under the brand name Enovid among others, is a progestin medication which was previously used in birth control pills and in the treatment of gynecological disorders but is now no longer marketed. It was available both alone and in combination with an estrogen. The medication is taken by mouth. (en)
rdfs:label
  • Noretinodrel (es)
  • Noretynodrel (en)
  • 异炔诺酮 (zh)
rdfs:seeAlso
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is owl:differentFrom of
is foaf:primaryTopic of
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