About: Ethisterone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Ethisterone, also known as ethinyltestosterone, pregneninolone, and anhydrohydroxyprogesterone and formerly sold under the brand names Proluton C and Pranone among others, is a progestin medication which was used in the treatment of gynecological disorders but is now no longer available. It was used alone and was not formulated in combination with an estrogen. The medication is taken by mouth.

Property Value
dbo:abstract
  • Ethisterone, also known as ethinyltestosterone, pregneninolone, and anhydrohydroxyprogesterone and formerly sold under the brand names Proluton C and Pranone among others, is a progestin medication which was used in the treatment of gynecological disorders but is now no longer available. It was used alone and was not formulated in combination with an estrogen. The medication is taken by mouth. Side effects of ethisterone include masculinization among others. Ethisterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has some androgenic and anabolic activity and no other important hormonal activity. Ethisterone was discovered in 1938 and was introduced for medical use in Germany in 1939 and in the United States in 1945. It was the second progestogen to be marketed, following injected progesterone in 1934, and was both the first orally active progestogen and the first progestin to be introduced. Ethisterone was followed by the improved and much more widely used and known progestin norethisterone in 1957. (en)
  • La etisterona es una hormona progestágena. La primera progestina activa, etisterona (pregneninolona, 17α-etiniltestosterona), el análogo 17α-etinil de la testosterona, sintetizada en 1938 por Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg y Arthur Serini en Schering AG en Berlín, fue comercializada en Alemania en 1939 como Proluton C y por Schering en los Estados Unidos en 1945 como Pranone.​​​​​ La también fue comercializada en los Estados Unidos desde los años 1950 hacia los años 1960 bajo una variedad de nombres comerciales por otras industrias farmacéuticas que habían sido miembros del cartel hormonal europeo pre-Segunda Guerra Mundial (Ciba, Organon International, Roussel Uclaf). (es)
  • 炔孕酮(英語:Ethisterone),也有称为乙炔睾酮(英語:ethinyltestosterone)、孕炔醇酮(英語:pregneninolone,商品名:Proluton C 或 Pranone等)是一种黄体制剂药物,过去被用于治疗一些妇科疾病,但现在已不再使用。 (zh)
dbo:alternativeName
  • Proluton C, Pranone, others (en)
dbo:casNumber
  • 434-03-7
dbo:chEBI
  • 34749
dbo:chEMBL
  • 241694
dbo:class
dbo:fdaUniiCode
  • P201BVY1MJ
dbo:pubchem
  • 5284557
dbo:thumbnail
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 6664174 (xsd:integer)
dbo:wikiPageLength
  • 32483 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1123032883 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • G03 (en)
dbp:atcSuffix
  • DC04 (en)
dbp:c
  • 21 (xsd:integer)
dbp:casNumber
  • 0434-03-07 (xsd:date)
dbp:chebi
  • 34749 (xsd:integer)
dbp:chembl
  • 241694 (xsd:integer)
dbp:chemspiderid
  • 4447612 (xsd:integer)
dbp:class
dbp:date
  • 2004-10-19 (xsd:date)
dbp:h
  • 28 (xsd:integer)
dbp:image
  • Ethisterone molecule ball.png (en)
dbp:iupacName
  • -17 (xsd:integer)
dbp:metabolites
  • • 5α-Dihydroethisterone (en)
dbp:o
  • 2 (xsd:integer)
dbp:pubchem
  • 5284557 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • C[C@]12CCCC=C1CC[C@@H]3[C@@H]2CC[C@]4C (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • CHNXZKVNWQUJIB-CEGNMAFCSA-N (en)
dbp:synonyms
  • Ethinyltestosterone; Ethynyltestosterone; Pregneninolone; Anhydrohydroxyprogesterone; Etisteron; Pregnin; Ethindrone (en)
dbp:tradename
  • Proluton C, Pranone, others (en)
dbp:unii
  • P201BVY1MJ (en)
dbp:url
dbp:verifiedfields
  • verified (en)
dbp:verifiedrevid
  • 461096491 (xsd:integer)
dbp:watchedfields
  • verified (en)
dbp:width
  • 225 (xsd:integer)
  • 235 (xsd:integer)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • 炔孕酮(英語:Ethisterone),也有称为乙炔睾酮(英語:ethinyltestosterone)、孕炔醇酮(英語:pregneninolone,商品名:Proluton C 或 Pranone等)是一种黄体制剂药物,过去被用于治疗一些妇科疾病,但现在已不再使用。 (zh)
  • Ethisterone, also known as ethinyltestosterone, pregneninolone, and anhydrohydroxyprogesterone and formerly sold under the brand names Proluton C and Pranone among others, is a progestin medication which was used in the treatment of gynecological disorders but is now no longer available. It was used alone and was not formulated in combination with an estrogen. The medication is taken by mouth. (en)
  • La etisterona es una hormona progestágena. La primera progestina activa, etisterona (pregneninolona, 17α-etiniltestosterona), el análogo 17α-etinil de la testosterona, sintetizada en 1938 por Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg y Arthur Serini en Schering AG en Berlín, fue comercializada en Alemania en 1939 como Proluton C y por Schering en los Estados Unidos en 1945 como Pranone.​​​​​ (es)
rdfs:label
  • Etisterona (es)
  • Ethisterone (en)
  • 炔孕酮 (zh)
rdfs:seeAlso
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
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is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
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