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- Pregnandiol ist ein hormonell wirkungsloses Abbauprodukt des Progesterons und anderer mit dem Progesteron verwandter Gestagene, die alle zur Gruppe der weiblichen Geschlechtshormone gehören. (de)
- Pregnanediol, or 5β-pregnane-3α,20α-diol, is an inactive metabolic product of progesterone. A test can be done to measure the amount of pregnanediol in urine, which offers an indirect way to measure progesterone levels in the body. From the urine of pregnant women from London clinics, Guy Frederic Marrian isolated a substance that contained two hydroxyl groups and could be converted into a diacetate with acetic anhydride. However, the formula had not been clearly clarified. Almost at the same time, Adolf Butenandt at the Chemical University Laboratory in Göttingen investigated the constituents of pregnant urine and clarified the structure of the diol. The name pregnandiol, coined by Butenandt, is derived from the Latin verb praegnans (pregnant, pregnant), or the English pregnant and pregnancy. This gave rise to the name pregnane for the underlying parent hydrocarbon. In 1936, Venning and Browne demonstrated the presence of pregnanediol, specifically the glucuronide of pregnanediol in pregnancy urine. Their study extracted pregnanediol from pregnancy urine and revealed that pregnanediol concentration in urine indicates the amount of progesterone excreted. Since progesterone levels indicate the functionality of a corpus luteum, and pregnanediol concentration represents 40-45% of the progesterone excreted, estimations of pregnanediol reveal the functionality of a corpus luteum. However, pregnanediol concentrations vary with menstrual cycle phases, so it is essential to consider the menstrual cycle phase when examining them. Furthermore, current research has demonstrated that pregnanediol concentration in urine is also a measure of ovarian activity. (en)
- 孕二醇或孕烷二醇（英語：Pregnanediol）或称为5β-孕烷-3α,20α-二醇（5β-pregnane-3α,20α-diol）是一种孕酮在体内的无活性的代谢产物。测试尿液中孕二醇的含量可以作为测量体内孕酮水平的一种间接方法。 (zh)
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- 5β-Pregnane-3α,20α-diol; Pregnandiol (en)
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- (3R,5R,8R,9S,10S,13S,14S,17S)-17-[(1S)-1-Hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol (en)
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- Pregnandiol ist ein hormonell wirkungsloses Abbauprodukt des Progesterons und anderer mit dem Progesteron verwandter Gestagene, die alle zur Gruppe der weiblichen Geschlechtshormone gehören. (de)
- 孕二醇或孕烷二醇（英語：Pregnanediol）或称为5β-孕烷-3α,20α-二醇（5β-pregnane-3α,20α-diol）是一种孕酮在体内的无活性的代谢产物。测试尿液中孕二醇的含量可以作为测量体内孕酮水平的一种间接方法。 (zh)
- Pregnanediol, or 5β-pregnane-3α,20α-diol, is an inactive metabolic product of progesterone. A test can be done to measure the amount of pregnanediol in urine, which offers an indirect way to measure progesterone levels in the body. (en)
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- Pregnandiol (de)
- Pregnanediol (en)
- 孕二醇 (zh)
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