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Proteomic investigation of acute and chronic hypoxia/reoxygenation responsive proteins and pathways in H9C2 cardiomyoblasts.
Öztuğ M, Kilinç E, Öztuğ Durer ZA, Baloğlu E
Turk J Biol, 48(3):192-202, 24 Apr 2024
Cited by: 0 articles | PMID: 39050708 | PMCID: PMC11265846
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Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers.
Khan HY, Nagasaka M, Aboukameel A, Alkhalili O, Uddin MH, Bannoura SF, Mzannar Y, Azar I, Beal EW, Tobon ME, Kim SH, Beydoun R, Baloglu E, Senapedis W, El-Rayes BF, Philip PA, Mohammad RM, Shields AF, Al Hallak MN, Azmi AS
Mol Cancer Ther, 22(12):1422-1433, 01 Dec 2023
Cited by: 1 article | PMID: 37703579 | PMCID: PMC10690049
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HIF-2α Controls Expression and Intracellular Trafficking of the α2-Subunit of Na,K-ATPase in Hypoxic H9c2 Cardiomyocytes.
Baloglu E
Biomedicines, 11(11):2879, 24 Oct 2023
Cited by: 0 articles | PMID: 38001879
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Hypoxia and HIF-1α Regulate the Activity and Expression of Na,K-ATPase Subunits in H9c2 Cardiomyoblasts.
Gurler B, Gencay G, Baloglu E
Curr Issues Mol Biol, 45(10):8277-8288, 12 Oct 2023
Cited by: 2 articles | PMID: 37886965 | PMCID: PMC10605391
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Hypoxic Stress-Dependent Regulation of Na,K-ATPase in Ischemic Heart Disease.
Baloglu E
Int J Mol Sci, 24(9):7855, 26 Apr 2023
Cited by: 6 articles | PMID: 37175562 | PMCID: PMC10177966
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Anticancer efficacy of KRASG12C inhibitors is potentiated by PAK4 inhibitor KPT9274 in preclinical models of KRASG12C mutant pancreatic and lung cancers
Khan HY, Nagasaka M, Aboukameel A, Alkhalili O, Uddin MH, Bannoura S, Mzannar Y, Azar I, Beal E, Tobon M, Kim S, Beydoun R, Baloglu E, Senapedis W, El-Rayes B, Philip PA, Mohammad RM, Shields AF, Al-Hallak MN, Azmi AS
bioRxiv, 27 Mar 2023
Cited by: 0 articles | PPR: PPR636466
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Hypoxia Aggravates Inhibition of Alveolar Epithelial Na-Transport by Lipopolysaccharide-Stimulation of Alveolar Macrophages.
Baloglu E, Velineni K, Ermis-Kaya E, Mairbäurl H
Int J Mol Sci, 23(15):8315, 27 Jul 2022
Cited by: 3 articles | PMID: 35955448 | PMCID: PMC9368968
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Oral eltanexor treatment of patients with higher-risk myelodysplastic syndrome refractory to hypomethylating agents.
Lee S, Mohan S, Knupp J, Chamoun K, de Jonge A, Yang F, Baloglu E, Shah J, Kauffman MG, Shacham S, Bhatnagar B
J Hematol Oncol, 15(1):103, 03 Aug 2022
Cited by: 7 articles | PMID: 35922861 | PMCID: PMC9351096
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In Search of a Sensor: How Does CO₂ Regulate Alveolar Ion Transport?
Baloğlu E, Mairbäurl H
Am J Respir Cell Mol Biol, 65(6):571-572, 01 Dec 2021
Cited by: 0 articles | PMID: 34348088 | PMCID: PMC8641802
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PAK4 and NAMPT as Novel Therapeutic Targets in Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, and Mantle Cell Lymphoma.
Khan HY, Uddin MH, Balasubramanian SK, Sulaiman N, Iqbal M, Chaker M, Aboukameel A, Li Y, Senapedis W, Baloglu E, Mohammad RM, Zonder J, Azmi AS
Cancers (Basel), 14(1):160, 29 Dec 2021
Cited by: 9 articles | PMID: 35008323 | PMCID: PMC8750170
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A phase 1 clinical trial of oral eltanexor in patients with relapsed or refractory multiple myeloma.
Cornell RF, Baz R, Richter JR, Rossi A, Vogl DT, Chen C, Shustik C, Alvarez MJ, Shen Y, Unger TJ, Ben-Shahar O, Wang H, Baloglu E, Senapedis W, Ma X, Landesman Y, Bai X, Bader J, Xu H, [...] Hofmeister CC
Am J Hematol, 97(2):E54-E58, 30 Nov 2021
Cited by: 9 articles | PMID: 34817872
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PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus.
Mpilla GB, Uddin MH, Al-Hallak MN, Aboukameel A, Li Y, Kim SH, Beydoun R, Dyson G, Baloglu E, Senapedis WT, Landesman Y, Wagner KU, Viola NT, El-Rayes BF, Philip PA, Mohammad RM, Azmi AS
Mol Cancer Ther, 20(10):1836-1845, 12 Jul 2021
Cited by: 10 articles | PMID: 34253597 | PMCID: PMC8492493
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The role of hypoxia-induced modulation of alveolar epithelial Na⁺- transport in hypoxemia at high altitude.
Baloglu E, Nonnenmacher G, Seleninova A, Berg L, Velineni K, Ermis-Kaya E, Mairbäurl H
Pulm Circ, 10(1 suppl):50-58, 01 Jul 2020
Cited by: 10 articles | PMID: 33110497 | PMCID: PMC7557693
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Anti-Cancer Activity of PAK4/NAMPT Inhibitor and Programmed Cell Death Protein-1 Antibody in Kidney Cancer.
Trott JF, Aboud OA, McLaughlin B, Anderson KL, Modiano JF, Kim K, Jen KY, Senapedis W, Chang H, Landesman Y, Baloglu E, Pili R, Weiss RH
Kidney360, 1(5):376-388, 01 May 2020
Cited by: 3 articles | PMID: 35224510 | PMCID: PMC8809296
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Publisher Correction: PAK4 inhibition improves PD-1 blockade immunotherapy.
Abril-Rodriguez G, Torrejon DY, Liu W, Zaretsky JM, Nowicki TS, Tsoi J, Puig-Saus C, Baselga-Carretero I, Medina E, Quist MJ, Garcia AJ, Senapedis W, Baloglu E, Kalbasi A, Cheung-Lau G, Berent-Maoz B, Comin-Anduix B, Hu-Lieskovan S, Wang CY, [...] Ribas A
Nat Cancer, 1(2):264, 01 Feb 2020
Cited by: 0 articles | PMID: 35122015
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Venetoclax response is enhanced by selective inhibitor of nuclear export compounds in hematologic malignancies.
Fischer MA, Friedlander SY, Arrate MP, Chang H, Gorska AE, Fuller LD, Ramsey HE, Kashyap T, Argueta C, Debler S, Byrne M, Villaume MT, Shaver AC, Senapedis W, Landesman Y, Baloglu E, Shacham S, Savona MR
Blood Adv, 4(3):586-598, 01 Feb 2020
Cited by: 31 articles | PMID: 32045477 | PMCID: PMC7013257
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Targeting XPO1 and PAK4 in 8505C Anaplastic Thyroid Cancer Cells: Putative Implications for Overcoming Lenvatinib Therapy Resistance.
Khan HY, Ge J, Nagasaka M, Aboukameel A, Mpilla G, Muqbil I, Szlaczky M, Chaker M, Baloglu E, Landesman Y, Mohammad RM, Azmi AS, Sukari A
Int J Mol Sci, 21(1):E237, 29 Dec 2019
Cited by: 14 articles | PMID: 31905765 | PMCID: PMC6982268
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PAK4 inhibition improves PD-1 blockade immunotherapy.
Abril-Rodriguez G, Torrejon DY, Liu W, Zaretsky JM, Nowicki TS, Tsoi J, Puig-Saus C, Baselga-Carretero I, Medina E, Quist MJ, Garcia AJ, Senapedis W, Baloglu E, Kalbasi A, Cheung-Lau G, Berent-Maoz B, Comin-Anduix B, Hu-Lieskovan S, Wang CY, [...] Ribas A
Nat Cancer, 1(1):46-58, 09 Dec 2019
Cited by: 70 articles | PMID: 34368780 | PMCID: PMC8340852
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PAK4-NAMPT Dual Inhibition as a Novel Strategy for Therapy Resistant Pancreatic Neuroendocrine Tumors.
Mpilla G, Aboukameel A, Muqbil I, Kim S, Beydoun R, Philip PA, Mohammad RM, Kamgar M, Shidham V, Senapedis W, Baloglu E, Li J, Dyson G, Xue Y, El-Rayes B, Azmi AS
Cancers (Basel), 11(12):E1902, 29 Nov 2019
Cited by: 13 articles | PMID: 31795447 | PMCID: PMC6966587
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Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer.
Sexton R, Mahdi Z, Chaudhury R, Beydoun R, Aboukameel A, Khan HY, Baloglu E, Senapedis W, Landesman Y, Tesfaye A, Kim S, Philip PA, Azmi AS
Int J Mol Sci, 20(19):E4826, 28 Sep 2019
Cited by: 21 articles | PMID: 31569391 | PMCID: PMC6801932
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Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia.
Mitchell SR, Larkin K, Grieselhuber NR, Lai TH, Cannon M, Orwick S, Sharma P, Asemelash Y, Zhang P, Goettl VM, Beaver L, Mims A, Puduvalli VK, Blachly JS, Lehman A, Harrington B, Henderson S, Breitbach JT, Williams KE, [...] Byrd JC
Blood Adv, 3(3):242-255, 01 Feb 2019
Cited by: 31 articles | PMID: 30692102 | PMCID: PMC6373756
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CBMT-04. INDUCING MITOCHONDRIAL OXIDATIVE STRESS AND TARGETING CELLULAR STRESS RESPONSE BY INHIBITION OF NAMPT, THE RATE LIMITING ENZYME IN THE NAD+ SALVAGE PATHWAY IN GLIOMA
Sharma P, Senepides W, Baloglu E, Puduvalli V
Neuro Oncol, 20(suppl 6):vi33-vi33, 01 Nov 2018
Cited by: 0 articles | PMCID: PMC6216935
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Functional Genome-wide Screening Identifies Targets and Pathways Sensitizing Pancreatic Cancer Cells to Dasatinib.
Chien W, Sudo M, Ding LW, Sun QY, Wuensche P, Lee KL, Hattori N, Garg M, Xu L, Zheng Y, Gery S, Wongphayak S, Yang H, Baloglu E, Shacham S, Kauffman M, Mori S, Koeffler HP
J Cancer, 9(24):4762-4773, 10 Dec 2018
Cited by: 23 articles | PMID: 30588262 | PMCID: PMC6299388
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Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression.
Aboukameel A, Muqbil I, Baloglu E, Senapedis W, Landesman Y, Argueta C, Kauffman M, Chang H, Kashyap T, Shacham S, Neggers JE, Daelemans D, Heath EI, Azmi AS
Oncotarget, 9(82):35327-35342, 19 Oct 2018
Cited by: 9 articles | PMID: 30450161 | PMCID: PMC6219671
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Nuclear-Cytoplasmic Transport Is a Therapeutic Target in Myelofibrosis.
Yan D, Pomicter AD, Tantravahi S, Mason CC, Senina AV, Ahmann JM, Wang Q, Than H, Patel AB, Heaton WL, Eiring AM, Clair PM, Gantz KC, Redwine HM, Swierczek SI, Halverson BJ, Baloglu E, Shacham S, Khorashad JS, [...] Deininger MW
Clin Cancer Res, 25(7):2323-2335, 18 Dec 2018
Cited by: 14 articles | PMID: 30563936 | PMCID: PMC6445677
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