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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K9me2 methyltransferase activity
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Accession:GO:0140947 term browser browse the term
Definition:Catalysis of the reaction: N6,N6-dimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the dimethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.
Synonyms:exact_synonym: histone H3K9me2 methylase activity;   histone dimethyl-lysine(H3K9) N-methyltransferase activity (H3-K9 specific)
 broad_synonym: histone H3-K9 trimethylation;   histone H3K9 trimethylation
 xref: EC:2.1.1.366;   RHEA:60280


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histone H3K9me2 methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Suv39h1 SUV39H1 histone lysine methyltransferase enables ISO MGI:1890396 (PMID:23451023) RGD PMID:23451023 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 enables ISO MGI:1890396 (PMID:23451023) RGD PMID:23451023 NCBI chr  X:141,792,589...141,795,257 JBrowse link
G Suv39h2 SUV39H2 histone lysine methyltransferase enables ISO MGI:1099440 (PMID:23451023) RGD PMID:23451023 NCBI chr17:74,756,290...74,775,332
Ensembl chr17:74,756,306...74,775,332 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      catalytic activity, acting on a protein 2508
        protein methyltransferase activity 104
          protein-lysine N-methyltransferase activity 69
            histone H3K9 methyltransferase activity 18
              histone H3K9me2 methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      transferase activity 2396
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              lysine N-methyltransferase activity 69
                protein-lysine N-methyltransferase activity 69
                  histone H3K9 methyltransferase activity 18
                    histone H3K9me2 methyltransferase activity 3
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