Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. (Q33837172): Difference between revisions

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@@ Property / cites work @@
+Abnormal lipoprotein pattern in patients with Alagille syndrome depends on Icterus severity
+Normal rank
+stated in: PubMed
reference URL: https://pubmed.ncbi.nlm.nih.gov/15671183
retrieved: 12 December 2020Timestamp +2020-12-12T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
based on heuristic: inferred from PubMed ID database lookup
-Timestamp
++2020-12-12T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / cites work @@
+Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation
+Normal rank
+stated in: PubMed
reference URL: https://pubmed.ncbi.nlm.nih.gov/15671183
retrieved: 12 December 2020Timestamp +2020-12-12T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
based on heuristic: inferred from PubMed ID database lookup
-Timestamp
++2020-12-12T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / cites work @@
+INDUCTION OF GALLSTONES IN MICE BY FEEDING A CHOLESTEROL-CHOLIC ACID CONTAINING DIET
+Normal rank
+stated in: PubMed
reference URL: https://pubmed.ncbi.nlm.nih.gov/15671183
retrieved: 12 December 2020Timestamp +2020-12-12T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
based on heuristic: inferred from PubMed ID database lookup
-Timestamp
++2020-12-12T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After

Revision as of 18:39, 1 April 2021

scientific article

Language	Label	Description	Also known as
English	Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ronald M. Evans

8

object named as

Ronald M Evans

0 references

author name string

Junichiro Sonoda

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ling Wa Chong

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Michael Downes

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Grant D Barish

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Sally Coulter

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Christopher Liddle

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Chih-Hao Lee

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

25 January 2005

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

102

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2198-2203

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

The enzymes, regulation, and genetics of bile acid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Software and methods for oligonucleotide and cDNA array data analysis

1 reference

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4 July 2018

Genetic defects in hepatobiliary transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Nuclear receptors and lipid physiology: opening the X-files

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Orphan nuclear receptors: the exotics of xenobiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Features of Alagille syndrome in 92 patients: frequency and relation to prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Unexpected clinical remission of cholestasis after rifampicin therapy in patients with normal or slightly increased levels of gamma-glutamyl transpeptidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Effects of long-term rifampicin administration in primary biliary cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Hypercholesterolemia and atherosclerosis in primary biliary cirrhosis: what is the risk?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

4 July 2018

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Resistance of SHP-null mice to bile acid-induced liver damage

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409481102

21 January 2018

Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

29 October 2018

Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548561

29 October 2018

Abnormal lipoprotein pattern in patients with Alagille syndrome depends on Icterus severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15671183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15671183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

INDUCTION OF GALLSTONES IN MICE BY FEEDING A CHOLESTEROL-CHOLIC ACID CONTAINING DIET

1 reference

https://pubmed.ncbi.nlm.nih.gov/15671183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0409481102

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

0 references

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