NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs (Q34581839)

3 August 2017

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title

NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs (English)

1 reference

3 August 2017

Vaquero A

1

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3 August 2017

Sternglanz R

series ordinal

2

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3 August 2017

Reinberg D

series ordinal

3

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3 August 2017

language of work or name

English

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publication date

1 August 2007

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3 August 2017

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3 August 2017

volume

26

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3 August 2017

issue

37

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3 August 2017

page(s)

5505-5520

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H4 acetylation does not replace H3 acetylation in chromatin remodelling and transcription activation of Adr1-dependent genes.

3 August 2017

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SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity

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Do protein motifs read the histone code?

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Genomic characterization reveals a simple histone H4 acetylation code.

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Yeast histone H4 N-terminal sequence is required for promoter activation in vivo

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Genome-wide analysis of HDAC function

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Sir2 blocks extreme life-span extension.

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

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Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

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Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

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Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

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SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex

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The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.

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The interaction between FOXO and SIRT1: tipping the balance towards survival

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Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

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Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes.

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Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

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Histone modifications: combinatorial complexity or cumulative simplicity?

21 January 2018

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mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila

21 January 2018

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Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene

21 January 2018

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Methylation of histone H4 by arginine methyltransferase PRMT1 is essential in vivo for many subsequent histone modifications

21 January 2018

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

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Histone H4 acetylation of euchromatin and heterochromatin is cell cycle dependent and correlated with replication rather than with transcription

21 January 2018

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Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair

21 January 2018

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Translating the Histone Code

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Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae

21 January 2018

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Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

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Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

21 January 2018

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Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.

21 January 2018

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Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing

21 January 2018

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Acetylation: a regulatory modification to rival phosphorylation?

21 January 2018

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SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

21 January 2018

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Histone acetylation and deacetylation in yeast

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Mapping global histone acetylation patterns to gene expression

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Splicing regulates NAD metabolite binding to histone macroH2A.

21 January 2018

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Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

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Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

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Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries

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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

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Histone H4 acetylated at lysine 16 and proteins of the Drosophila dosage compensation pathway co-localize on the male X chromosome through mitosis.

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Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are members of an ancient protein superfamily

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Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation

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Sirtuins in aging and age-related disease.

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Negative control of p53 by Sir2alpha promotes cell survival under stress

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Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4.

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21 January 2018

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Poly(ADP-ribose) polymerases: managing genome stability

21 January 2018

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Acetylation of yeast histone H4 lysine 16: a switch for protein interactions in heterochromatin and euchromatin

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Crystal structure of a SIR2 homolog-NAD complex

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Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

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Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

21 January 2018

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Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

21 January 2018

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Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications

21 January 2018

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Histone modifications: signalling receptors and potential elements of a heritable epigenetic code

21 January 2018

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The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

21 January 2018

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Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations

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SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

21 January 2018

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The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p

21 January 2018

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Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

21 January 2018

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A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast

21 January 2018

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 January 2018

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Chromatin assembly: a basic recipe with various flavours

21 January 2018

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Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

21 January 2018

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Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases

21 January 2018

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

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Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

21 January 2018

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Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination

21 January 2018

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Histone acetyltransferases

21 January 2018

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Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome

21 January 2018

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Histone variants meet their match

21 January 2018

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Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry

21 January 2018

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The biochemistry of sirtuins.

21 January 2018

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SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

21 January 2018

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Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

21 January 2018

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The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

21 January 2018

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Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast

21 January 2018

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SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

21 January 2018

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SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Histone H4-K16 acetylation controls chromatin structure and protein interactions

21 January 2018

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Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

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Mass spectrometric quantification of acetylation at specific lysines within the amino-terminal tail of histone H4

21 January 2018

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A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16

21 January 2018

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Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4.

21 January 2018

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Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine

21 January 2018

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Acetylation of histones and transcription-related factors

21 January 2018

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Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin

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Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin

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An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

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CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i

21 January 2018

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Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast

21 January 2018

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Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei

21 January 2018

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Histone H4 acetylation in human cells. Frequency of acetylation at different sites defined by immunolabeling with site-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Histone acetylation and an epigenetic code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

The constantly changing face of chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Nuclear export modulates the cytoplasmic Sir2 homologue Hst2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Acetylation in histone H3 globular domain regulates gene expression in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

Histone H4 acetylation in plant heterochromatin is altered during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Chromatin Fiber Folding: Requirement for the Histone H4 N-terminal Tail

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Methyl deficiency, alterations in global histone modifications, and carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

The diversity of acetylated proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Males absent on the first (MOF): from flies to humans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Acetylpolyamine amidohydrolase from Mycoplana ramosa: gene cloning and characterization of the metal-substituted enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Genome-wide histone modifications: gaining specificity by preventing promiscuity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210617

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210617

1 reference

Dimensions Publication ID

3 August 2017

1031480740

0 references

1 reference