Car9 (carbonic anhydrase 9) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Car9 (carbonic anhydrase 9) Mus musculus
Analyze
Symbol: Car9
Name: carbonic anhydrase 9
RGD ID: 1315035
MGI Page MGI
Description: Predicted to enable carbonate dehydratase activity; molecular function activator activity; and zinc ion binding activity. Acts upstream of or within morphogenesis of an epithelium and secretion. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; gut; and heart. Human ortholog(s) of this gene implicated in hepatitis B; lung non-small cell carcinoma; and renal cell carcinoma. Orthologous to human CA9 (carbonic anhydrase 9).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CA; CA-IX; Ca9; CAIX; carbonate dehydratase IX; carbonic anhydrase IX; membrane antigen MN homolog; MN/C; MN/CA9
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,507,026 - 43,513,729 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,506,966 - 43,513,729 (+)EnsemblGRCm39 Ensembl
GRCm38443,507,026 - 43,513,729 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,506,966 - 43,513,729 (+)EnsemblGRCm38mm10GRCm38
MGSCv37443,519,898 - 43,526,597 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,528,107 - 43,534,829 (+)NCBIMGSCv36mm8
Celera443,540,895 - 43,547,584 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,10-phenanthroline  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-methylumbelliferyl beta-D-galactoside  (ISO)
4-nitrophenol  (EXP)
acetamide  (ISO)
acetazolamide  (ISO)
acrylamide  (ISO)
amphotericin B  (ISO)
ampicillin  (ISO)
antirheumatic drug  (ISO)
Archazolid B  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
betulin  (ISO)
betulinic acid  (ISO)
bezafibrate  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A5  (ISO)
bortezomib  (ISO)
butanal  (ISO)
butyric acid  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
captan  (EXP)
carbonates  (ISO)
CAY10591  (ISO)
CGP 52608  (ISO)
chloric acid  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cobalt(2+) sulfate  (ISO)
copper(II) chloride  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
desferrioxamine B  (ISO)
diarsenic trioxide  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
folpet  (EXP)
gemfibrozil  (ISO)
Genipin  (ISO)
heptanal  (ISO)
hexanal  (ISO)
hydroquinone  (ISO)
iron(III) citrate  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
LY294002  (ISO)
molibresib  (ISO)
molybdate  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nitric acid  (ISO)
Nonidet P-40  (ISO)
O-methyleugenol  (ISO)
octanal  (ISO)
oryzalin  (ISO)
oxaliplatin  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perchlorate  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
serpentine asbestos  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sotorasib  (ISO)
sulfamic acid  (ISO)
sulfates  (ISO)
sulindac  (ISO)
temozolomide  (ISO)
thiram  (ISO)
trametinib  (ISO)
tributylstannane  (ISO)
Triptolide  (ISO)
tungstate  (ISO)
Tungsten carbide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors. Birle DC and Hedley DW, Cancer Res. 2007 Feb 15;67(4):1735-43.
2. Hypomethylation of the MN/CA9 promoter and upregulated MN/CA9 expression in human renal cell carcinoma. Cho M, etal., Br J Cancer. 2001 Aug 17;85(4):563-7.
3. Immunotargeting of human cervical carcinoma xenograft expressing CA IX tumor-associated antigen by 125I-labeled M75 monoclonal antibody. Chrastina A, etal., Neoplasma. 2003;50(1):13-21.
4. New Gene Variants Associated with the Risk of Chronic HBV Infection. Fan M, etal., Virol Sin. 2020 Aug;35(4):378-387. doi: 10.1007/s12250-020-00200-x. Epub 2020 Apr 15.
5. p16 is consistently expressed in endometrial tubal metaplasia. Horree N, etal., Cell Oncol. 2007;29(1):37-45.
6. Hypoxia and angiogenesis in endometrioid endometrial carcinogenesis. Horree N, etal., Cell Oncol. 2007;29(3):219-27.
7. GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON. Hoskin PJ, etal., Br J Cancer. 2003 Oct 6;89(7):1290-7.
8. Carbonic anhydrase IX, a marker of hypoxia: correlation with clinical outcome in transitional cell carcinoma of the bladder. Hussain SA, etal., Oncol Rep. 2004 May;11(5):1005-10.
9. Response of CAIX and CAXII to in vitro re-oxygenation and clinical significance of the combined expression in NSCLC patients. Ilie M, etal., Lung Cancer. 2013 Oct;82(1):16-23. doi: 10.1016/j.lungcan.2013.07.005. Epub 2013 Jul 30.
10. pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma. Kuchuk O, etal., Oncoimmunology. 2018 Mar 26;7(7):e1445452. doi: 10.1080/2162402X.2018.1445452. eCollection 2018.
11. Tumor carbonic anhydrase 9 expression is associated with the presence of lymph node metastases in uterine cervical cancer. Lee S, etal., Cancer Sci. 2007 Mar;98(3):329-33. Epub 2007 Jan 12.
12. Hypoxia and its downstream targets in DMBA induced mammary carcinoma: protective role of Semecarpus anacardium nut extract. Mathivadhani P, etal., Chem Biol Interact. 2007 Apr 5;167(1):31-40. Epub 2007 Jan 10.
13. MGDs mouse GO annotations MGD data from the GO Consortium
14. MGD IEA MGD IEA
15. Carbonic anhydrase IX is highly expressed in hereditary nonpolyposis colorectal cancer. Niemelä AM, etal., Cancer Epidemiol Biomarkers Prev. 2007 Sep;16(9):1760-6. doi: 10.1158/1055-9965.EPI-07-0080.
16. Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma. Patard JJ, etal., Int J Cancer. 2008 May 7;123(2):395-400.
17. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
18. Mouse MP Annotation Import Pipeline RGD automated import pipeline
19. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
20. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
21. Induction of antigen specific cellular immunity by vaccination with peptides from MN/CA IX in renal cell carcinoma. Shimizu K, etal., Oncol Rep. 2003 Sep-Oct;10(5):1307-11.
22. Changes in the expression and/or activation of regulatory proteins in rat hearts adapted to chronic hypoxia. Strniskova M, etal., Gen Physiol Biophys. 2006 Mar;25(1):25-41.
23. HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome. Trastour C, etal., Int J Cancer. 2007 Apr 1;120(7):1451-8.
24. Gene Expression Profiles Associated with the Presence of a Fibrotic Focus and the Growth Pattern in Lymph Node-Negative Breast Cancer. Van den Eynden GG, etal., Clin Cancer Res. 2008 May 15;14(10):2944-2952.
25. Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients. Zavada J, etal., Br J Cancer. 2003 Sep 15;89(6):1067-71.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12454846   PMID:12466851   PMID:12477932   PMID:14604546   PMID:14681479   PMID:15385577   PMID:16141072   PMID:16141073  
PMID:16217040   PMID:16245156   PMID:16396925   PMID:16602821   PMID:16719910   PMID:16924128   PMID:17362527   PMID:17418408   PMID:18003750   PMID:19074859   PMID:19564335   PMID:20399150  
PMID:20562862   PMID:20573196   PMID:21306648   PMID:21547424   PMID:21677750   PMID:21873635   PMID:23233153   PMID:23441228   PMID:23945394   PMID:24697899   PMID:24789143   PMID:25623234  
PMID:26152355   PMID:28262664   PMID:28692057   PMID:28748627   PMID:31078621   PMID:31202927   PMID:31777931   PMID:31905844   PMID:33432108   PMID:35242281   PMID:35377412   PMID:35773253  
PMID:37279265   PMID:37373220  


Genomics

Comparative Map Data
Car9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,507,026 - 43,513,729 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,506,966 - 43,513,729 (+)EnsemblGRCm39 Ensembl
GRCm38443,507,026 - 43,513,729 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,506,966 - 43,513,729 (+)EnsemblGRCm38mm10GRCm38
MGSCv37443,519,898 - 43,526,597 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,528,107 - 43,534,829 (+)NCBIMGSCv36mm8
Celera443,540,895 - 43,547,584 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.05NCBI
CA9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,673,928 - 35,681,159 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,673,928 - 35,681,159 (+)EnsemblGRCh38hg38GRCh38
GRCh37935,673,925 - 35,681,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,663,915 - 35,671,152 (+)NCBINCBI36Build 36hg18NCBI36
Build 34935,663,914 - 35,671,152NCBI
Celera935,607,463 - 35,614,702 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,629,523 - 35,636,764 (+)NCBIHuRef
CHM1_1935,673,743 - 35,680,984 (+)NCBICHM1_1
T2T-CHM13v2.0935,694,579 - 35,701,811 (+)NCBIT2T-CHM13v2.0
Car9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,559,024 - 62,565,626 (+)NCBIGRCr8
mRatBN7.2557,763,234 - 57,769,838 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,763,206 - 57,769,838 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,743,112 - 59,749,748 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,561,925 - 61,568,564 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,533,190 - 61,539,753 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0559,008,277 - 59,015,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,008,933 - 59,015,528 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,533,527 - 63,540,129 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,986,413 - 59,993,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1559,986,589 - 59,992,484 (+)NCBI
Celera556,343,808 - 56,350,416 (+)NCBICelera
Cytogenetic Map5q22NCBI
Ca9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955472619,245 - 625,051 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955472619,084 - 625,570 (-)NCBIChiLan1.0ChiLan1.0
CA9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21188,906,190 - 88,913,457 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1988,912,119 - 88,919,393 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0935,525,877 - 35,533,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1936,328,205 - 36,335,474 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,328,303 - 36,335,340 (+)Ensemblpanpan1.1panPan2
CA9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,205,619 - 52,211,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,205,668 - 52,211,267 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,773,252 - 50,778,851 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01153,270,515 - 53,276,220 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1153,270,614 - 53,276,220 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,815,201 - 51,820,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,798,686 - 51,804,281 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01152,500,820 - 52,506,421 (+)NCBIUU_Cfam_GSD_1.0
Ca9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,124,669 - 167,131,057 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365243,672,541 - 3,678,433 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365243,672,393 - 3,678,630 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,394,306 - 236,400,822 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,393,727 - 236,400,994 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,118,816 - 264,126,024 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,921,530 - 44,929,504 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1244,921,665 - 44,928,831 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603842,026,370 - 42,034,593 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ca9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248685,109,846 - 5,116,949 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248685,110,602 - 5,131,167 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Car9
258 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1015
Count of miRNA genes:571
Interacting mature miRNAs:675
Transcripts:ENSMUST00000030183, ENSMUST00000124114, ENSMUST00000126750, ENSMUST00000128232, ENSMUST00000129996, ENSMUST00000138073, ENSMUST00000154251
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse

Markers in Region
Car9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38443,508,734 - 43,509,004UniSTSGRCm38
Celera443,542,613 - 43,542,883UniSTS
Cytogenetic Map4B1UniSTS
cM Map423.05UniSTS
Car9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000030183   ⟹   ENSMUSP00000030183
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,506,966 - 43,513,729 (+)Ensembl
GRCm38.p6 Ensembl443,506,966 - 43,513,729 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124114
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,507,024 - 43,513,729 (+)Ensembl
GRCm38.p6 Ensembl443,507,024 - 43,513,729 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126750
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,508,543 - 43,509,035 (+)Ensembl
GRCm38.p6 Ensembl443,508,543 - 43,509,035 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128232
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,507,877 - 43,508,974 (+)Ensembl
GRCm38.p6 Ensembl443,507,877 - 43,508,974 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129996
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,508,937 - 43,512,455 (+)Ensembl
GRCm38.p6 Ensembl443,508,937 - 43,512,455 (+)Ensembl
Ensembl Acc Id: ENSMUST00000138073   ⟹   ENSMUSP00000114493
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,507,312 - 43,513,058 (+)Ensembl
GRCm38.p6 Ensembl443,507,312 - 43,513,058 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,512,132 - 43,512,942 (+)Ensembl
GRCm38.p6 Ensembl443,512,132 - 43,512,942 (+)Ensembl
RefSeq Acc Id: NM_139305   ⟹   NP_647466
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39443,507,026 - 43,513,725 (+)NCBI
GRCm38443,507,026 - 43,513,725 (+)NCBI
MGSCv37443,519,898 - 43,526,597 (+)RGD
Celera443,540,895 - 43,547,584 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006537831   ⟹   XP_006537894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39443,507,956 - 43,513,729 (+)NCBI
GRCm38443,507,956 - 43,513,729 (+)NCBI
Sequence:
RefSeq Acc Id: NP_647466   ⟸   NM_139305
- Peptide Label: precursor
- UniProtKB: Q8K1G1 (UniProtKB/Swiss-Prot),   Q8VDE4 (UniProtKB/Swiss-Prot),   Q8VHB5 (UniProtKB/Swiss-Prot),   Q3UUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006537894   ⟸   XM_006537831
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000114493   ⟸   ENSMUST00000138073
Ensembl Acc Id: ENSMUSP00000030183   ⟸   ENSMUST00000030183
Protein Domains
Alpha-carbonic anhydrase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VHB5-F1-model_v2 AlphaFold Q8VHB5 1-437 view protein structure

Promoters
RGD ID:6883226
Promoter ID:EPDNEW_M5064
Type:multiple initiation site
Name:Car9_1
Description:Mus musculus carbonic anhydrase 9 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38443,507,026 - 43,507,086EPDNEW
RGD ID:6834998
Promoter ID:MM_KWN:37348
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000016053,   OTTMUST00000016060
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,521,439 - 43,521,939 (+)MPROMDB
RGD ID:6835000
Promoter ID:MM_KWN:37350
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:OTTMUST00000016061
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,524,866 - 43,525,366 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2447188 AgrOrtholog
Ensembl Genes ENSMUSG00000028463 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030183 ENTREZGENE
  ENSMUST00000030183.10 UniProtKB/Swiss-Prot
  ENSMUST00000138073.2 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:230099 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2447188 ENTREZGENE
NCBI Gene 230099 ENTREZGENE
PANTHER PTHR18952 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18952:SF18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Car9 PhenoGen
PROSITE ALPHA_CA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1ECK8_MOUSE UniProtKB/TrEMBL
  CAH9_MOUSE UniProtKB/Swiss-Prot
  F6XXU0_MOUSE UniProtKB/TrEMBL
  Q3TLN7_MOUSE UniProtKB/TrEMBL
  Q3UUZ9 ENTREZGENE, UniProtKB/TrEMBL
  Q8K1G1 ENTREZGENE
  Q8VDE4 ENTREZGENE
  Q8VHB5 ENTREZGENE
UniProt Secondary Q8K1G1 UniProtKB/Swiss-Prot
  Q8VDE4 UniProtKB/Swiss-Prot